4,214 research outputs found

    Boundary regularity for the Poisson equation in reifenberg-flat domains

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    This paper is devoted to the investigation of the boundary regularity for the Poisson equation {{cc} -\Delta u = f & \text{in} \Omega u= 0 & \text{on} \partial \Omega where ff belongs to some Lp(Ω)L^p(\Omega) and Ω\Omega is a Reifenberg-flat domain of Rn.\mathbb R^n. More precisely, we prove that given an exponent α∈(0,1)\alpha\in (0,1), there exists an ε>0\varepsilon>0 such that the solution uu to the previous system is locally H\"older continuous provided that Ω\Omega is (ε,r0)(\varepsilon,r_0)-Reifenberg-flat. The proof is based on Alt-Caffarelli-Friedman's monotonicity formula and Morrey-Campanato theorem

    Strategic Interaction and Spatial Multiplier Effects in Local Growth Control Policies: The California Housing Market

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    Since the 1970s, growth controls spread across many metropolitan regions in the United States. Several studies address the effects of local growth controls on housing markets, particularly its price effect, which is induced by rising construction cost, constrained housing supply, improved amenities, and market reorientation of homebuilders. However, only few studies explicitly address inter-jurisdictional spatial spillovers and strategic interaction of policy-makers of different jurisdictions in the design of growth control policies. This study focuses on two housing market outcomes, supply of new housing and market orientation, and utilizes a spatial econometric framework to systematically investigate local and global spatial spillovers giving rise to spatial multiplier effects. Preliminary results suggest that market orientation of new home building is primarily influenced by population growth and building permit caps, with positive spillovers at the local level only. For the supply of new housing, however, the models seem to suggest positive global spillover effects. However, there is additional indication of a potential relevance of including spatial heterogeneity in the model specification. Specifically, a north-south disparity or a coastal-inland disparity may have non-negligible impacts with concurrent implications for policy-making.spatial spillovers, growth controls, housing supply, market orientation, Public Economics, C21, H23, H73, R31,

    Wounds That Will Not Heal Pervasive Cellular Reprogramming in Cancer

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    There has been an explosion of articles on epithelial-mesenchymal transition and other modes of cellular reprogramming that influence the tumor microenvironment. Many controversies exist and remain to be resolved. The interest of the pathologists in the molecular and functional parallels between wound healing and the developing tumor stroma has its earliest origin in the writings of Rudolph Virchow in the 19th century. Since then, most of the focus has been primarily on the dynamics of the extracellular matrix; however, new interest has been redirected toward deciphering and understanding the enigmatic, yet elegant, plasticity of the cellular components of the proliferating epithelia and stroma and how they are reciprocally influenced. Citing several examples from breast cancer research, we will trace how these perspectives have unfolded in the pages of The American Journal of Pathology and other investigative journals during the past century, their impact, and where the field is headed

    Simultaneous dual-frequency radio observations of S5 0716+714: A search for intraday variability with the Korean VLBI Network

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    This study aims to search for the existence of intraday variability (IDV) of BL Lac object S5 0716+714 at high radio frequencies for which the interstellar scintillation effect is not significant. Using the 21-meter radio telescope of the Korean VLBI Network (KVN), we present results of multi-epoch simultaneous dual-frequency radio observations. Single-dish observations of S5 0716+714 were simultaneously conducted at 21.7 GHz (K-band) and 42.4 GHz (Q-band), with a high cadence of 30-60 minute intervals.We observed four epochs between December 2009 and June 2010. Over the whole set of observation epochs, S5 0716+714 showed significant inter-month variations in flux density at both the K- and Q-bands, with modulation indices of approximately 19% for the K-band and approximately 36% for the Q-band. In all epochs, no clear intraday variability was detected at either frequency. The source shows monotonic flux density increase in epochs 1 and 3 and monotonic flux density decrease in epochs 2 and 4. In the flux density increasing phases, the flux densities at the Q-band increase more rapidly. In the decreasing phase, no significant flux density difference is seen at the two frequencies. The situation could be different close to flux density peaks that we did not witness in our observations. We find an inverted spectrum with mean spectral indices of -0.57+-0.13 in epoch 1 and -0.15+-0.11 in epoch 3. On the other hand, we find relatively steep indices of +0.24+-0.14 and +0.17+-0.18 in epochs 2 and 4, respectively. We conclude that the frequency dependence of the variability and the change of the spectral index are caused by source-intrinsic effects rather than by any extrinsic scintillation effect.Comment: 6 pages and 4 figures and 4 table

    Thermally enhanced oxygen scavengers including a transition metal and a free radical scavenger

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    An oxygen scavenging system comprising a free radical scavenger (e.g., .alpha.-tocopherol, trimethylhydroquinone, ubiquinol, carotenoids, flavonoids, etc. and mixtures thereof) and a transition metal (e.g., iron (II), copper, manganese, cobalt, etc. and mixtures thereof) in a medium is generally provided. The medium containing the antioxidant and the transition metal has been thermally processed by heating to at least about 150.degree. F. for at least about 10 minutes. Methods of removing oxygen from an environment surrounded by a medium containing the oxygen scavenging system and methods of making the oxygen scavenging system in a medium are also provided

    Modeling, system identification, and control of ASTREX

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    The modeling, system identification and controller design aspects of the ASTREX precision space structure are presented in this work. Modeling of ASTREX is performed using NASTRAN, TREETOPS and I-DEAS. The models generated range from simple linear time-invariant models to nonlinear models used for large angle simulations. Identification in both the time and frequency domains are presented. The experimental set up and the results from the identification experiments are included. Finally, controller design for ASTREX is presented. Simulation results using this optimal controller demonstrate the controller performance. Finally the future directions and plans for the facility are addressed
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